NFL Week 5 picks, predictions: New York Giants vs. Carolina Panthers | Is Saquon Barkley or Christian McCaffrey the difference? ESPN, CBS Sports, Fox Sports

The New York Giants (1-3), led by quarterback Eli Manning, running back Saquon Barkley and wide receiver Odell Beckham, meet the Carolina Panthers (2-1), led by quarterback Cam Newton, in a Week 5 NFL game on Sunday, October 7, 2018 (10/7/18) at Bank of America Stadium in Charlotte, North Carolina.

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